Protein Info for Psest_1697 in Pseudomonas stutzeri RCH2

Annotation: Gamma-aminobutyrate permease and related permeases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 47 to 66 (20 residues), see Phobius details amino acids 88 to 108 (21 residues), see Phobius details amino acids 125 to 143 (19 residues), see Phobius details amino acids 154 to 176 (23 residues), see Phobius details amino acids 198 to 220 (23 residues), see Phobius details amino acids 241 to 262 (22 residues), see Phobius details amino acids 284 to 309 (26 residues), see Phobius details amino acids 341 to 363 (23 residues), see Phobius details amino acids 370 to 389 (20 residues), see Phobius details amino acids 409 to 431 (23 residues), see Phobius details amino acids 437 to 455 (19 residues), see Phobius details PF00324: AA_permease" amino acids 19 to 458 (440 residues), 413.3 bits, see alignment E=1.3e-127 PF13520: AA_permease_2" amino acids 23 to 435 (413 residues), 119.3 bits, see alignment E=2.2e-38

Best Hits

Swiss-Prot: 46% identical to YTNA_BACSU: Uncharacterized amino acid permease YtnA (ytnA) from Bacillus subtilis (strain 168)

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 94% identity to psa:PST_2613)

Predicted SEED Role

"Aromatic amino acid transport protein AroP" in subsystem Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GKD3 at UniProt or InterPro

Protein Sequence (464 amino acids)

>Psest_1697 Gamma-aminobutyrate permease and related permeases (Pseudomonas stutzeri RCH2)
MTAETLHTGSLQRGLKNRHIQLIALGGAIGTGLFLGSAGVLRSAGPSMILGYAIGGFIAF
LIMRQLGEMIVEEPVAGSFSHFAHKYGGGYAGFLSGWNYWVLYVLVGMAELTAVGKYVQF
WWPEVPTWATAAAFFVLINLINLSNVKAFGETEFWFAIVKVAAIVGMILLGLFLLVSGKG
GEQASISNLWSHGGFFPNGFSGMLLALAIIMFSFGGLELVGITAAEAAEPKTVIPKAINQ
VVYRILIFYIGALTVLLALYPWDALLLTLGAAGDPYSGSPFVQIFSLIGSDTAAHLLNFV
VLTAALSVYNSGVYCNSRMLYGLAEQGDAPRSLMKINSRGVPVLAVGVSALVTLLCVAVN
YLFPQGALELLMSLAVAALVINWAMISLAHLKFRRAMQQQGVEPSFKAFWFPLSNYLCLA
FVAGILIIMLWLPGIRMSVFAIPVWVGFLWLCYRLRARLLARAV