Protein Info for PGA1_c16560 in Phaeobacter inhibens DSM 17395

Annotation: extracellular ligand binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 24 to 353 (330 residues), 269.6 bits, see alignment E=9e-84 PF13433: Peripla_BP_5" amino acids 25 to 355 (331 residues), 76.3 bits, see alignment E=3.8e-25 PF01094: ANF_receptor" amino acids 57 to 341 (285 residues), 30.4 bits, see alignment E=3.4e-11

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 79% identity to rde:RD1_0540)

Predicted SEED Role

"Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EZH0 at UniProt or InterPro

Protein Sequence (378 amino acids)

>PGA1_c16560 extracellular ligand binding domain-containing protein (Phaeobacter inhibens DSM 17395)
MTTLKTMALATAVSTLALAAGAETKIGMITTLSGGGAGLGVDVRDGFMLAMEQAGRDDIE
VVIEDDQRKPESAVQIADQMIQSEKVDIMTGIIWSNLAMAVVPAATAQGVFYLSPNAGPS
ALAGKRCHENYFNVAWQNDNLHEAAGAYANDAGLKNSYILAPNYPAGKDALTGYKRMYQG
DLAGETYTKLGQTDYAAEIAQIRASGADSVYFFLPGGMGISFLKQYADSGVDLPVVGPAF
SFDQGILQAVGGAALGIKNTSQWNKDLDNPANTAFVAAFEQKYERLPSLYASQGYDTANL
ILSALDKASVDDKEAFRAALKAAEFESVRGDFKFGDNHHPIQNIYVREVIQEGDVFTNKI
IATGLENHADAYAAECKM