Protein Info for PGA1_c16380 in Phaeobacter inhibens DSM 17395

Updated annotation (from data): citrulline utilization hydrolase
Rationale: Specifically important for: L-Citrulline. This enzyme is distantly related to characterized arginine deiminases (see PF02274) and has conserved catalytic residues. It might be a citrullinase.
Original annotation: Uncharacterized protein conserved in bacteria containing a pentein-type domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF19420: DDAH_eukar" amino acids 18 to 299 (282 residues), 313.2 bits, see alignment E=8.5e-98

Best Hits

KEGG orthology group: None (inferred from 81% identity to sit:TM1040_1164)

Predicted SEED Role

"Amidinotransferase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EX15 at UniProt or InterPro

Protein Sequence (309 amino acids)

>PGA1_c16380 citrulline utilization hydrolase (Phaeobacter inhibens DSM 17395)
MSQLQAPGAVVMIRPHHFCSNPETRDDNAFQTLADDTADVTSAQAQAEFDGAVTALRGAG
VSVHVFDDTGTETPDSVFPNNWFSTHAGGHVAVYPMYAANRRKERRWDVIELLKRDYRVQ
DVIDYSGLEQDGLALEGTGAMVLDHIGRIAYTVKSNRADPVLLERFCTHFNFEPMVFEAR
DAQGRDVYHTNVLMGIGTDYALICLDMITDPTRRAEVAARLEETGRRVIDLTPEQIAGFA
GNALELTGHSRLLALSSRAAEVLRADQITIIERSATLLPLSIPTIETAGGSVRCMLAAIH
LSPRERTQS