Protein Info for Psest_0160 in Pseudomonas stutzeri RCH2

Annotation: C-terminal peptidase (prc)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF22694: CtpB_N-like" amino acids 41 to 93 (53 residues), 38.6 bits, see alignment 3e-13 TIGR00225: C-terminal processing peptidase" amino acids 61 to 379 (319 residues), 354.6 bits, see alignment E=2.6e-110 PF00595: PDZ" amino acids 106 to 174 (69 residues), 36.7 bits, see alignment E=1.2e-12 PF13180: PDZ_2" amino acids 107 to 178 (72 residues), 48.5 bits, see alignment E=2.2e-16 PF17820: PDZ_6" amino acids 122 to 176 (55 residues), 45.4 bits, see alignment 1.3e-15 PF03572: Peptidase_S41" amino acids 205 to 371 (167 residues), 195.9 bits, see alignment E=9e-62

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 96% identity to psa:PST_4082)

Predicted SEED Role

"Carboxyl-terminal protease (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GG81 at UniProt or InterPro

Protein Sequence (439 amino acids)

>Psest_0160 C-terminal peptidase (prc) (Pseudomonas stutzeri RCH2)
MLHLRRFARPSTLALAILLGMQGGAWAQQPPAEAAVPSSKAPLPLDELRTFAEVLDRIKA
AYVEPVDDKTLLENAIKGMLSNLDPHSAYLEPEAFAELQESTSGEFGGLGIEVGMEDGFI
KVVSPIDDTPASKAGIEAGDLIVKIDGQPTKGLSMMDAIGKMRGKPGSSISLTLVREGGQ
PFDVKLKRAVIKVRSVRSQILEPGYGYLRVTQFQVNSGEEVGKALAKLKKDNDGKKLNGL
VLDLRNNPGGVLQAAVEISDHFLTKGLIVYTKGRIANSELRFNADPADASEGVPLVVLIN
GGSASASEIVAGALQDHKRGVVMGTDSFGKGSVQTVLPLNNDRALKLTTALYYTPNGRSI
QAQGIEPDIKVERAKLTREQAADGFREADLAGHLGNGNGGPDRPTATQIASDSPRPQDDD
YQLGQALNLLKGLNLTRGQ