Protein Info for PGA1_c15670 in Phaeobacter inhibens DSM 17395

Annotation: putative beta-lactamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 PF00144: Beta-lactamase" amino acids 15 to 397 (383 residues), 187.3 bits, see alignment E=2.2e-59

Best Hits

KEGG orthology group: None (inferred from 67% identity to sil:SPO1960)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EZB2 at UniProt or InterPro

Protein Sequence (403 amino acids)

>PGA1_c15670 putative beta-lactamase (Phaeobacter inhibens DSM 17395)
MDAARLEHIRTWQHRYVDQRKYAGSSLLINRNGKERYFHAAGQRNIVENLPFTRDTVARI
YSMTKPVTSLALMMLLERGLLHLDMPVSEFLPEFNGMRCLVDGATDITQTRSCRPPTLHE
LLTHTSGLSYPFNPGVLSEEMSKTDLMFKPGQGPLAAQVLELAALPLAFEPGQRWEYSVG
IDVIGRVIEVVTGESLGAMLKREIFDPLGMERTGFRSEETTGNLLASLYSPLSDDAMALN
DAQQGADSLRLIDSYDDTPFDTAEMHSGGGGLLSTIDDYMRFAELIRLRGALGKDHLISP
QIIDFMCQNHLPGDIASMGPQSFAEQPMDGMGFGLGGAVVLDPARARCPGSVGDFSWGGM
ASTFFWVDPVLDLSVVFFTQLAPSSSYPSRAELKALVHGAVTS