Protein Info for PGA1_c14920 in Phaeobacter inhibens DSM 17395

Annotation: transcription-repair-coupling factor Mfd

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1155 PF17757: UvrB_inter" amino acids 123 to 207 (85 residues), 67.8 bits, see alignment 2.2e-22 TIGR00580: transcription-repair coupling factor" amino acids 137 to 1074 (938 residues), 1014.3 bits, see alignment E=0 PF02559: CarD_TRCF_RID" amino acids 475 to 530 (56 residues), 69.5 bits, see alignment 6.2e-23 PF04851: ResIII" amino acids 597 to 753 (157 residues), 36.2 bits, see alignment E=1.8e-12 PF00270: DEAD" amino acids 597 to 758 (162 residues), 81.5 bits, see alignment E=1.9e-26 PF00271: Helicase_C" amino acids 797 to 901 (105 residues), 61.5 bits, see alignment E=2.7e-20 PF03461: TRCF" amino acids 1002 to 1095 (94 residues), 93.2 bits, see alignment E=3.2e-30

Best Hits

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ELT5 at UniProt or InterPro

Protein Sequence (1155 amino acids)

>PGA1_c14920 transcription-repair-coupling factor Mfd (Phaeobacter inhibens DSM 17395)
MAQRAITAGGAPEGFDARLILKEAASSDAPVVHVARDDKRMEATRAALAFFAPDMPVISF
PGWDCLPYDRVSPNADIAAARMATLAALVHQMPGQFVLLTTLNAATQRVPARQVLKDAAF
VAEVDRRIDEEALRGYLTRMGFTKSPTVMEPGDFAVRGGIIDIYPPGQSGPVRLDLFGDV
LDGARRFDPATQRTTEKLSVVELAPVSEVILDEAAVTRFRQNYRIEFGAAGTDDPLYEAV
SAGRKYQGIEHWLPFFHERLETLFDYLPQATVTLDDQVTPARLARWDSIVDQYETRKIAM
AQKGRMDTVYKPVPPGLLYLDDDAWEAAIGDHRVIQFHPLPQASGPGVIDAGGRIGRNFS
PERQLESVSLFKSLADHIKARMQVGPVVVASYSEGARERLTGLIEDEGLAEVIAINDGTR
IGKSGLHLAVWALEHGFETDDLTVISEQDVLGDRLIRAPKKRRKAENFLTETQSLSPGDL
VVHVDHGIGRYKGLEVVTAAGAAHECILLEYAEHSKLYLPVENIELLSKYGHDEGLLDRL
GGGAWQAKKAKLKERIREMADRLIRVAAERALRKAPMMDPPPHAWEEFSARFPYQETDDQ
LRAISEVMEDLQSGSPMDRLICGDVGFGKTEVAMRAAFIAAMSGVQVAIVAPTTLLARQH
AAAFAQRFRGFPLEVRQLSRFVTAKEAAKTREGMAKGTIDIVVGTHALLAKSVRFQNLGL
LIIDEEQHFGVAHKERLKQMRSDIHVLTLTATPIPRTLQLSLTGVRDLSIIGTPPVDRLA
IRTYVSEFDAVTIREALLREHYRGGQSFYVVPRITDLPDVEAFLQEQLPELSYVVAHGQL
AAGDLDDRMNAFYDGKFDVLLATTIVESGLDIPTANTMVVHRADMFGLAQLYQIRGRVGR
SKTRAYAYLTTKPRVRLTPGAEKRLRVLGSLDTLGAGFSLASQDLDIRGAGNLLGEEQSG
QMRDVGYELYQSMLEEAIAKIKSGELEGLSGSDDQWAPQINLGVPVLIPENYVPDLDVRL
GLYRRLSDLSTKVELEGFAAELIDRFGALPKEVNTLMLVVRIKAMCKRAGIAKLDGGPKG
ATIQFHNDKFASPQGLVEFIQAQDGLAKVKDNKIVVRRDWKKDSDKIKGAFAIARDLAEK
VVAEKKKAKAKAKSG