Protein Info for PGA1_c13960 in Phaeobacter inhibens DSM 17395

Annotation: putative mechanosensitive ion channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 829 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 201 to 220 (20 residues), see Phobius details amino acids 242 to 266 (25 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 323 to 341 (19 residues), see Phobius details amino acids 353 to 370 (18 residues), see Phobius details amino acids 406 to 422 (17 residues), see Phobius details amino acids 428 to 448 (21 residues), see Phobius details amino acids 467 to 490 (24 residues), see Phobius details amino acids 513 to 535 (23 residues), see Phobius details amino acids 556 to 578 (23 residues), see Phobius details amino acids 585 to 614 (30 residues), see Phobius details PF12607: DUF3772" amino acids 130 to 188 (59 residues), 67.5 bits, see alignment 1e-22 PF00924: MS_channel_2nd" amino acids 601 to 668 (68 residues), 87.7 bits, see alignment E=6.5e-29 PF21082: MS_channel_3rd" amino acids 676 to 758 (83 residues), 66.6 bits, see alignment E=3.4e-22

Best Hits

KEGG orthology group: None (inferred from 63% identity to sit:TM1040_1438)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EYV9 at UniProt or InterPro

Protein Sequence (829 amino acids)

>PGA1_c13960 putative mechanosensitive ion channel protein (Phaeobacter inhibens DSM 17395)
MIALMRGFVKCLAGLVLLISLAFPALAQLDARAKSYYEDWLRTANRAENVIDASRASNLA
LEQLRSELADFRQTFQVKRGENGERIQTLQGQLDALGAAPGEGEEEPEDIAQLRAALTQQ
LNQLKVPRIVAEEAYSRADGLINEVDKIVRERLTKRLFERGTSPLNPEHWPGALRDLVHA
SRAVGNETLSQLRNDTTSERISGDLVGLIAVLLIGLLLITRGRSWAHRAGDYLRRYGARG
TGVWTFVVSLLQVLLPLIGVIFLAAAVDLSGILGVRGSIILDSVPAWAFIILSFHWLGEQ
LYANQIENDLLPVQEGNQAETRFLIDMMAVILVLQDAFATIERIQNIPESSAAVYAFPLI
TCAALILLRLHRIGAKQRQAQSDEDGEEGAIAAGANRIIAVVRRSIYLLGFAGPVLAAIG
YLNAAESVIYPSMLTLAVLAGLFVLHRFLGDLYGFVSGKGMAARDSLFAALIGFALALLA
LPLLALIWGARVADLTELWSNFLEGFQVGDTRISPTAFITFVAIFAVGYGLTRLVQGSLR
NALLPKTRIDVGGQNAIASGMGYVGIFLAALVAVSMAGLDLSSLAIVAGALSVGIGFGLQ
TIVSNFVSGIILLVERPVSKGDWIEVGGLMGYVRDISVRSTRIETFDRTDVIVPNSDLIT
GTVTNYTRGNTVGRVIVPVGVSYGTDPRKVEAILMEVAKAHPMVLMNPPPSVVFQGFGAD
SLNFEIRAILRDVNWVLSVKSDMNYDIARRFDEAGIEIPFAQRDIWIRNPDALAAAATEA
AQGIKAPEAAVTASNPPPSPSKKRPDRPDLDDLSSADDGDGSEDGDADR