Protein Info for HP15_1345 in Marinobacter adhaerens HP15

Annotation: sulphate ABC transporter, permease protein CysT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 22 to 51 (30 residues), see Phobius details amino acids 75 to 99 (25 residues), see Phobius details amino acids 111 to 133 (23 residues), see Phobius details amino acids 145 to 169 (25 residues), see Phobius details amino acids 201 to 219 (19 residues), see Phobius details amino acids 225 to 248 (24 residues), see Phobius details amino acids 256 to 279 (24 residues), see Phobius details TIGR00969: sulfate ABC transporter, permease protein" amino acids 19 to 282 (264 residues), 334.6 bits, see alignment E=4.8e-104 TIGR02139: sulfate ABC transporter, permease protein CysT" amino acids 22 to 284 (263 residues), 398.7 bits, see alignment E=1.3e-123 PF00528: BPD_transp_1" amino acids 89 to 286 (198 residues), 75.9 bits, see alignment E=1.8e-25

Best Hits

Swiss-Prot: 65% identical to CYST_SALTY: Sulfate transport system permease protein CysT (cysU) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02046, sulfate transport system permease protein (inferred from 76% identity to maq:Maqu_1372)

MetaCyc: 65% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysU (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysT" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PJC3 at UniProt or InterPro

Protein Sequence (290 amino acids)

>HP15_1345 sulphate ABC transporter, permease protein CysT (Marinobacter adhaerens HP15)
MATTDVSERPSKRLSAPATKRVLPGFGLSLGISLFFISLVLLLPISGLFIRAAGMGWEQF
WFVITDPRVVASYKVTALAALAASLFNCVFGLLMAWVLVRYEFPGKRLLDAIMDLPFALP
TAVAGITLATLFAENGWYGQYLADLGIEVAFTPLGIVVAMAFTSVPFVVRTVQPVLEEMA
PEDEEAAMSLGASDMTVFRKILFPTLWPAVVTGGALSFARSLGEYGAVIFIAGNSPYISE
VISLMIFVRLEEYDFPAASAIAAVVMTVSLLLLLAINVWQGRYLKRLHGG