Protein Info for HP15_1344 in Marinobacter adhaerens HP15

Annotation: thiosulfate transporter subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR00971: sulfate ABC transporter, sulfate-binding protein" amino acids 32 to 340 (309 residues), 446 bits, see alignment E=3.6e-138 PF01547: SBP_bac_1" amino acids 49 to 285 (237 residues), 49.8 bits, see alignment E=1e-16 PF13531: SBP_bac_11" amino acids 55 to 289 (235 residues), 110.4 bits, see alignment E=2.4e-35 PF13416: SBP_bac_8" amino acids 122 to 302 (181 residues), 31.1 bits, see alignment E=4.3e-11 PF13343: SBP_bac_6" amino acids 143 to 311 (169 residues), 25 bits, see alignment E=2.4e-09

Best Hits

Swiss-Prot: 60% identical to CYSP_SALTY: Thiosulfate-binding protein (cysP) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02048, sulfate transport system substrate-binding protein (inferred from 76% identity to maq:Maqu_1373)

MetaCyc: 60% identical to thiosulfate/sulfate ABC transporter periplasmic binding protein CysP (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate and thiosulfate binding protein CysP" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PJC2 at UniProt or InterPro

Protein Sequence (344 amino acids)

>HP15_1344 thiosulfate transporter subunit (Marinobacter adhaerens HP15)
MPNSIFSGSKARKGLWFSALALAFSLTGPASAQERELLNSSYDIARELFAEYNVLFQDYW
KEKTGETVDIQQSHAGSSKQARAILQGLGADVVTYNQVTDVNILAERGNLIPEDWASRLP
NNSSPYYSTMAFLVREGNPKNIQNWDDLIREDVELIMPNPKTSGNGRYTYLAALGFAQDK
FGDDQEKIDAFLSDLLGQVKVFDSGGRGATTTFVERGLGDVLLTFESEVNNIPALNPDKN
FQVVVPKVSFLAEFPVTWIDKNIEKKGTEELAQAYLKHLYSEEAQRMLAGFNYRVHNETV
KAEVADKFPELKLMPIQDIAGSWENAMETHFASGGKLDQLQRRR