Protein Info for PGA1_c13820 in Phaeobacter inhibens DSM 17395
Annotation: 4'-phosphopantetheinyl transferase-like protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"4'-phosphopantetheinyl transferase (EC 2.7.8.-)" in subsystem Fatty Acid Biosynthesis FASII (EC 2.7.8.-)
KEGG Metabolic Maps
- Aminophosphonate metabolism
- Glycerophospholipid metabolism
- High-mannose type N-glycan biosynthesis
- Nucleotide sugars metabolism
- Sphingolipid metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.7.8.-
Use Curated BLAST to search for 2.7.8.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7DPU9 at UniProt or InterPro
Protein Sequence (257 amino acids)
>PGA1_c13820 4'-phosphopantetheinyl transferase-like protein (Phaeobacter inhibens DSM 17395) MPVSDHHVPVPALQPGQVHLWQGTVGCGALADLDPTVLSPSEQARMASIANTDARALYAA SHVALRHVLTAYDGRPARNLRFRTAEGGKPGLVDGRGLSFNLSHSGQMLLIAVADDCELG VDIEQQRGGHRSEAVARRFFAPEEYTALATCPVHLRSDYFTQIWALKEAYIKATGQGLAQ PLQGFAVKCLEDRAELMRCDIGRPDDWTLVTWTPTPGYKAALAAQRPALEVHHFDLAEAD IPSPAGSLFRKPHSGRP