Protein Info for HP15_1329 in Marinobacter adhaerens HP15

Annotation: DEAD/DEAH box helicase domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 PF00270: DEAD" amino acids 26 to 192 (167 residues), 162.9 bits, see alignment E=1.2e-51 PF04851: ResIII" amino acids 41 to 186 (146 residues), 35.5 bits, see alignment E=2e-12 PF00271: Helicase_C" amino acids 227 to 335 (109 residues), 97.6 bits, see alignment E=1e-31 PF03880: DbpA" amino acids 385 to 455 (71 residues), 89.4 bits, see alignment E=2.5e-29

Best Hits

KEGG orthology group: K05591, ATP-independent RNA helicase DbpA [EC: 3.6.4.13] (inferred from 73% identity to maq:Maqu_0969)

Predicted SEED Role

"ATP-dependent 23S rRNA helicase DbpA"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PIL8 at UniProt or InterPro

Protein Sequence (457 amino acids)

>HP15_1329 DEAD/DEAH box helicase domain protein (Marinobacter adhaerens HP15)
MSSFNDFGLSTAMCSNLNQLGFAQPTEIQAKAIAPGLAGKDIIAMAKTGSGKTAAFGISL
VERLNPRLFAVQALVLCPTRELADQVAKAIRELARARDNIKVLTLCGGVAIGPQIGSLSH
GAHIVVGTPGRIQDHLRKQTLSLVRLKTVVLDEADRMLDMGFQEAMEDILSQTPPSRQTM
MFSATWPAPIRELSKQYQKSPVDVRAEDTGDNPDIEELFYEVSPQSKSDAIVALLSERQP
ESCIVFCTTKQQCDDMAAELGERGFSALPLHGDLEQRDRDSVLVRFGNQSCSILVATDVA
ARGLDIKSLPLVINAEPARDPEVHTHRIGRTGRAGEQGHAVTFCTPAQGHKITRIESERG
RSVTWGDTEKLLATPLKSVVPAMKTLCIAGGRKDKVRPGDVLGALTGEAGLPGKAVGKID
LFDHQCFVAVEKSLAAKALARLESGKVKGRKIRVRYA