Protein Info for PGA1_c13740 in Phaeobacter inhibens DSM 17395

Annotation: long-chain-fatty-acid- CoA ligase IcfB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 transmembrane" amino acids 59 to 80 (22 residues), see Phobius details PF00501: AMP-binding" amino acids 12 to 368 (357 residues), 283.4 bits, see alignment E=2.7e-88 PF13193: AMP-binding_C" amino acids 424 to 500 (77 residues), 56.5 bits, see alignment E=4.3e-19

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7ELH0 at UniProt or InterPro

Protein Sequence (533 amino acids)

>PGA1_c13740 long-chain-fatty-acid- CoA ligase IcfB (Phaeobacter inhibens DSM 17395)
MLSKHNLLTNFLEQAASDYPHSTAAEDSTRQLTFAEMRDRAQRVAQLLKQQGVARGDHVV
LCMSNSVGFCVAFWATLYAGAAAVPLNTDTKAAKLAFVLGDCAATAVIHDDDQSAKITQS
LQDAGSDAAMISFGAETAFSTALDGAGDRPQQAPATVLDQDLAAIIYTSGSTGNPKGVML
SHLNMTSAARSVAEYLGYQATDRIFCAIPMTFDYGLHQLTMATLTGACLLVEPSFARPLF
ALQRLAKSGATVFPVVPTMVPLIAPLAARYDFSDVRSISSTAAALHAPFIDQLEVIFPNA
TVFSMYGLTECHRCTYLDPAELTRRRTSVGKAIPNTELWVVDADGNSHRRNATGELVIRG
STVMKGYLNNPEKTAEKLRPGPMPGEQVLYTGDTCRLDEDGFVYFISRSDDILKVAGEKV
APSEIETALIAHPDVDEVCALGVDHPVYGQQCCAVVSGPDVSSPDSARALKTWCADRLEA
HVVPARILVVEALARNGNGKVDRHLLREWLDAGTSSGNQSDAVSRSHADPVPS