Protein Info for PGA1_c13190 in Phaeobacter inhibens DSM 17395

Updated annotation (from data): ABC transporter for D-Sorbitol, permease component 1
Rationale: Specific phenotypes on D-Sorbitol; D-Sorbitol.
Original annotation: ABC transporter permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 72 to 97 (26 residues), see Phobius details amino acids 108 to 131 (24 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 184 to 207 (24 residues), see Phobius details amino acids 214 to 233 (20 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 90 to 258 (169 residues), 54.4 bits, see alignment E=6.9e-19

Best Hits

KEGG orthology group: K10229, sorbitol/mannitol transport system permease protein (inferred from 90% identity to sit:TM1040_0429)

MetaCyc: 66% identical to polyol ABC-type transporter permease component MtlG (Pseudomonas fluorescens)
7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]

Predicted SEED Role

"Various polyols ABC transporter, permease component 2" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.M2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EYP2 at UniProt or InterPro

Protein Sequence (276 amino acids)

>PGA1_c13190 ABC transporter for D-Sorbitol, permease component 1 (Phaeobacter inhibens DSM 17395)
MARAVTPRRKAINTALAWAVGLLIFFPILWTILTSFKTEAQAISDPPVFLFFDWTLENYS
VVQERSDYMRFLWNSVIIAGGSTILGIIIAVPAAWSMAFVPSKRTKDILLWMLSTKMLPA
VGVLYPIYILFIKMGLLDNRFGLVVVLMLINLPIIVWMLYTYFKEIPGEILEAARMDGAT
LKEEILYVLTPMAIPGIASTLLLNIILAWNEAFWTLNLTAAKAAPLTAFIASYSSPEGLF
YAKLSAASTMAIAPILILGWFSQKQLVSGLTFGAVK