Protein Info for PGA1_c01320 in Phaeobacter inhibens DSM 17395

Annotation: elongation factor Tu

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 TIGR00485: translation elongation factor Tu" amino acids 1 to 390 (390 residues), 734.8 bits, see alignment E=1.9e-225 PF00009: GTP_EFTU" amino acids 10 to 198 (189 residues), 211.1 bits, see alignment E=2.3e-66 TIGR00231: small GTP-binding protein domain" amino acids 13 to 143 (131 residues), 53.3 bits, see alignment E=2.8e-18 PF03144: GTP_EFTU_D2" amino acids 222 to 291 (70 residues), 64.8 bits, see alignment E=1.5e-21 PF03143: GTP_EFTU_D3" amino acids 295 to 389 (95 residues), 136 bits, see alignment E=1.2e-43

Best Hits

Swiss-Prot: 94% identical to EFTU_RUEST: Elongation factor Tu (tuf1) from Ruegeria sp. (strain TM1040)

KEGG orthology group: K02358, elongation factor Tu (inferred from 94% identity to sit:TM1040_2434)

Predicted SEED Role

"Translation elongation factor Tu" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9GJT8 at UniProt or InterPro

Protein Sequence (391 amino acids)

>PGA1_c01320 elongation factor Tu (Phaeobacter inhibens DSM 17395)
MAKEKFERTKPHVNIGTIGHVDHGKTTLTAAITKYFGDFKAYDQIDGAPEEKARGITIST
AHVEYETEARHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLGRQ
VGIPKMVVFMNKVDQVDDEELLELVEMEIRELLSSYDYPGDDIPIVAGSALAAMEGNKPE
IGEEKIKELMAAVDDYIDTPERAVDQPFLMPIEDVFSISGRGTVVTGRVERGVINVGDSI
EIVGIRDTSTTTCTGVEMFRKLLDRGEAGDNIGALLRGVDRDGVERGQVLCKPGSVKPHT
KFEAEAYILTKEEGGRHTPFFANYRPQFYFRTTDVTGTVTLPEGTEMVMPGDNLKFDVEL
IAPIAMENGLRFAIREGGRTVGAGVVSKITD