Protein Info for HP15_1266 in Marinobacter adhaerens HP15

Annotation: flavodoxin/nitric oxide synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 201 TIGR01755: NAD(P)H:quinone oxidoreductase, type IV" amino acids 8 to 199 (192 residues), 149.3 bits, see alignment E=6.7e-48 PF03358: FMN_red" amino acids 43 to 144 (102 residues), 38.1 bits, see alignment E=6e-14

Best Hits

Swiss-Prot: 62% identical to NQOR_PSEAE: NAD(P)H dehydrogenase (quinone) (PA0949) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03809, Trp repressor binding protein (inferred from 83% identity to maq:Maqu_0913)

Predicted SEED Role

"Flavoprotein WrbA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PIF5 at UniProt or InterPro

Protein Sequence (201 amino acids)

>HP15_1266 flavodoxin/nitric oxide synthase (Marinobacter adhaerens HP15)
MSDQLPYVLVLFYSRTGQTAELASQIGRGVARVTGMEARLRAVPPVSPDTEASLPAVPDS
GAPYASKSDLANCAGLAIGSPTRFGNMAAPLKHFLDTTGDLWLSGTLEGKPAGAFTSTGS
LHGGQETTLMTMMMPLLHHGMVVCGLPYSEKSLGETDTGGTPYGPTHWAGTGEQQPLSTH
EKALCQAFGERLARLALKLAD