Protein Info for HP15_1231 in Marinobacter adhaerens HP15

Annotation: periplasmic tail-specific proteinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 707 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF17804: TSP_NTD" amino acids 43 to 230 (188 residues), 208.1 bits, see alignment E=3.7e-65 TIGR00225: C-terminal processing peptidase" amino acids 198 to 555 (358 residues), 311.9 bits, see alignment E=2.5e-97 PF00595: PDZ" amino acids 239 to 317 (79 residues), 37.3 bits, see alignment E=7.6e-13 PF03572: Peptidase_S41" amino acids 361 to 534 (174 residues), 169.1 bits, see alignment E=1.6e-53 PF11818: DUF3340" amino acids 538 to 681 (144 residues), 136.3 bits, see alignment E=2.5e-43

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 84% identity to maq:Maqu_2491)

Predicted SEED Role

"Periplasmic protease"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PHN0 at UniProt or InterPro

Protein Sequence (707 amino acids)

>HP15_1231 periplasmic tail-specific proteinase (Marinobacter adhaerens HP15)
MCKAMTVALLLSAPLGLHANVETPDVYEPVAPTIDQARANILIARQLQFTHFRDLGISDE
LSGDVFDAYLDYLDGQRIYLSQDDIAKFDKIRTQLGSALKTGQLQPGFDIYNLVQQRIIE
RLQFALETIDKGIDTLDFSANESILVDRSKADWESNAKALDDLWVKRIKNAVLAQRLNGA
EDEAIVETLRRRYEGQLKRAYQARSEDAFQAYMNAFTGMWDPHTSYFSPRTSENFNINMS
LSLEGIGAVLQSDNEYTKVVRLVPGGPASKQGQLEPADRIVSVAQEDEKPVNVIGWRLDE
VVDLIRGPRNSTVTLEVIPANASDETITETIAIKRDEVKLEEQSASKDTIRLERGGKEYT
IGVITIPTFYADFQAMQAGDPNYKSTTRDVRNLIAELEADGVDGLVMDLRNNGGGALHEA
NDLVGLFIDKGPTVQIRNANNDVQVLNDEDPSVAYDGPLVVLTNRMSASASEIFAGAIQD
YGRGLVVGSQTFGKGTVQAVRPLNHGQLKITQSKFYRVSGGSTQHKGVIPDIEIPSRIDK
TRIGEDALDHALPWDQIEAVPHTRYFDFSGIIDELRKRHEERFSTNPEFSLLQQEIDFLT
KQRATDSVSLNLEERRAEHEQIERTRLTIANARRELKGQTPFESLEDLEDWQDQQAADLN
STDEELDFVIREGGHIMADMLDLDNRMASILDPQQFAAQSPAAAVTR