Protein Info for PGA1_c12490 in Phaeobacter inhibens DSM 17395

Annotation: heat shock protein (HSP 70)-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 PF00012: HSP70" amino acids 7 to 224 (218 residues), 48.4 bits, see alignment E=4.6e-17

Best Hits

KEGG orthology group: K04046, hypothetical chaperone protein (inferred from 71% identity to sit:TM1040_1020)

Predicted SEED Role

"Putative heat shock protein YegD" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DPH5 at UniProt or InterPro

Protein Sequence (416 amino acids)

>PGA1_c12490 heat shock protein (HSP 70)-like protein (Phaeobacter inhibens DSM 17395)
MTHPNTLGIDFGTSNSAAGVAVNGRPWLIEAEPGETTLPTAVFFDLDSRRMTIGRRATRA
LINGDEGRFMRALKSLLGTPLMHEKRRLNGELVDFVTIVARFLAELKARAEAATSQTFTH
ALSGRPVLFHSKDTTRNAQAEVDLRACYMAAGFEDVRFMLEPEAALRSARAQSGIGLIVD
IGGGTSDFTAFEQTAEGTTRILASHGVRLGGTDFDRQLSIDHVMPLLGRGSAIRNSFGGG
SLPAPNRLFNDLATWQMIPFLYAADSRRAAQDLARNAEEPEKLARLVSVLEDELGHDLAF
AVERGKIASNQPGERNAVIDLKVLERGLSVPLVAEGLQRSLAGDIAEITACARETLRRAD
LREEQVSRVVLVGGSALLRGVQQQMQQLCPEAELYTENAMTAVADGLALASGSAFA