Protein Info for PGA1_c12250 in Phaeobacter inhibens DSM 17395

Annotation: monovalent cation/proton antiporter subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 53 (22 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 107 to 126 (20 residues), see Phobius details amino acids 132 to 151 (20 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 206 to 231 (26 residues), see Phobius details amino acids 242 to 264 (23 residues), see Phobius details amino acids 279 to 297 (19 residues), see Phobius details amino acids 304 to 324 (21 residues), see Phobius details amino acids 330 to 349 (20 residues), see Phobius details amino acids 370 to 389 (20 residues), see Phobius details amino acids 409 to 428 (20 residues), see Phobius details amino acids 470 to 490 (21 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 128 to 419 (292 residues), 148.2 bits, see alignment E=1.5e-47

Best Hits

KEGG orthology group: K05561, multicomponent K+:H+ antiporter subunit D (inferred from 74% identity to sit:TM1040_1540)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EVY9 at UniProt or InterPro

Protein Sequence (520 amino acids)

>PGA1_c12250 monovalent cation/proton antiporter subunit D (Phaeobacter inhibens DSM 17395)
MNHLVIAPIVLPAIVAPFIIMVLRFHLDLQRIFSVASSVLVLCLTLALAAQAADGTVQVY
ELGDWPAPFGIVLVLDRLSAMMIVLTSVLALAVVLYAIGTGWDSRGANFHALFQFQIMGI
LGAFMTGDAFNLFVFFEVLLIASYGLMIHAGGAKRFQAGVQYVVYNLLGSTLFLFALGTI
YAVTGTLNMADLAVRVAEMSGEETALLRVGAVMLLLVFAIKAAVLPLHFWLPASYSHAPL
PVAALFAIMTKVGAYSILRVYTLIFGPDVAISEGLVGDWLLPAALLTLAVGAVGVLGSRE
IGRLVAFGAITSMGTLLISIALFTPAATGAALYYIVHSTLATALMFLIADQVMERQGGAV
AAMRLMPQSGLLSIMFFVAAIALAGMPPLSGFIGKLLVMDAARDHDLVWWIWAVILVGSL
VTIIGLARAGTLIFWKSHGLPDNDSDADTEADSDDLLDGSATAAPAATPVLPLVVCFGLM
TALALLTIFAGPMKRYADATAAQLFTPTAYIETVLGGGSK