Protein Info for PGA1_c12130 in Phaeobacter inhibens DSM 17395

Annotation: DNA-damage-inducible protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 49 to 70 (22 residues), see Phobius details amino acids 99 to 121 (23 residues), see Phobius details amino acids 140 to 160 (21 residues), see Phobius details amino acids 168 to 190 (23 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 246 to 265 (20 residues), see Phobius details amino acids 278 to 304 (27 residues), see Phobius details amino acids 316 to 338 (23 residues), see Phobius details amino acids 358 to 379 (22 residues), see Phobius details amino acids 390 to 409 (20 residues), see Phobius details amino acids 415 to 434 (20 residues), see Phobius details TIGR00797: MATE efflux family protein" amino acids 23 to 416 (394 residues), 232 bits, see alignment E=5.9e-73 PF01554: MatE" amino acids 23 to 183 (161 residues), 55.9 bits, see alignment E=2.2e-19 amino acids 246 to 398 (153 residues), 47 bits, see alignment E=1.2e-16

Best Hits

KEGG orthology group: K03327, multidrug resistance protein, MATE family (inferred from 78% identity to sit:TM1040_1551)

Predicted SEED Role

"DNA-damage-inducible protein F"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EYE8 at UniProt or InterPro

Protein Sequence (443 amino acids)

>PGA1_c12130 DNA-damage-inducible protein F (Phaeobacter inhibens DSM 17395)
MTGTSAAGSEPISHKRVLKIALPIVLSNATVPILGAVDTGVVGQMGQAAPIGAVGIGAVI
LATIYWIFGFLRMGTTGLAAQARGAGDWAETGALLTRGVLLAFAAGAVFIAGQAAVFWGA
FALAPASAEVEGLARSYLEIRIWGAPATIALYAVTGWLIAVERTRGVFVLQIWMNGLNIL
LDLWFVLGLGWGVEGVAAATLIAEWSGLALGLWLCRDAFAGRQWRNWARVFDPARLKRMM
QVNGDIMIRSVLLTGSFTTFLFIGADLGDVTLAANQVLLQFVEITAFALDGFAFSAEALV
GSAVGAKARMQLRRAAIVASQWGVGGAIVLGLLFWLGGGWLIDVMSTSEAVRAAGRDYLI
WAAVLPLISVASYMFDGIYIGATWTRDMRIAMLQSVAIYVVALVVLVPSLGNHGLWASLM
VLNVARGVTLGLRYPRLEAQVGS