Protein Info for PGA1_c11740 in Phaeobacter inhibens DSM 17395

Annotation: rhomboid protein-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 transmembrane" amino acids 15 to 35 (21 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 99 to 117 (19 residues), see Phobius details amino acids 123 to 144 (22 residues), see Phobius details amino acids 151 to 175 (25 residues), see Phobius details amino acids 192 to 212 (21 residues), see Phobius details PF01694: Rhomboid" amino acids 62 to 212 (151 residues), 115.5 bits, see alignment E=1.1e-37

Best Hits

KEGG orthology group: None (inferred from 70% identity to sil:SPO3011)

Predicted SEED Role

"FIG056164: rhomboid family serine protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EL01 at UniProt or InterPro

Protein Sequence (258 amino acids)

>PGA1_c11740 rhomboid protein-like protein (Phaeobacter inhibens DSM 17395)
MFPIRDHNPSGRTPYVTYALICANVAIFALTYFGYDSPRRLTALYNAYALLPAEVTSGYD
LKTLLTSTFLHGSWMHLGGNMLFLWIFGDNMEDEMGHVPFIAFYLVSGIGAGLIHVASAP
YSLVPLVGASGAIAGVMGGYLLLFPRARVDILLILIIYFRVFSIPAFVMLGVWLGMQFLG
GIGSDPQAGGVAYWAHAGGFGVGLVLTIPLWLRRGGPAYWGKTHGQPPHPEVSYSTSRIP
RVARKSASDDRRNSPWDR