Protein Info for HP15_1125 in Marinobacter adhaerens HP15

Annotation: glutathione S-transferase YghU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 transmembrane" amino acids 20 to 34 (15 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details PF13410: GST_C_2" amino acids 84 to 150 (67 residues), 39.5 bits, see alignment E=9.5e-14 PF14497: GST_C_3" amino acids 87 to 161 (75 residues), 21.8 bits, see alignment E=3.5e-08 PF00043: GST_C" amino acids 90 to 158 (69 residues), 30.5 bits, see alignment E=7e-11

Best Hits

Predicted SEED Role

"Glutathione S-transferase (EC 2.5.1.18)" in subsystem Glutathione: Non-redox reactions (EC 2.5.1.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.18

Use Curated BLAST to search for 2.5.1.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PGV3 at UniProt or InterPro

Protein Sequence (206 amino acids)

>HP15_1125 glutathione S-transferase YghU (Marinobacter adhaerens HP15)
MKIKPNSKIPALLDQSVSPSIRVFESGAILLYLAEKFNAFIPTDTAERAECLSWLFWQMG
SALMLGGGFGHFYAYAPEKYEYPINRFAMEVKRQLDVLDRRLADNRFIAGNEYTIADMAI
WPWYGALVANKIYEAAEFLETHTYTNVLRWTHEIAERPAVQRGRMDNRAWHPEEAGCRQA
ESRENQSQCAHQSGASVPVHQAGLRL