Protein Info for HP15_1119 in Marinobacter adhaerens HP15

Annotation: efflux transporter, RND family, MFP subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 372 signal peptide" amino acids 12 to 13 (2 residues), see Phobius details amino acids 37 to 42 (6 residues), see Phobius details transmembrane" amino acids 14 to 36 (23 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 57 to 369 (313 residues), 191.9 bits, see alignment E=7.1e-61 PF13533: Biotin_lipoyl_2" amino acids 84 to 118 (35 residues), 26.7 bits, see alignment 7.4e-10 PF16576: HlyD_D23" amino acids 85 to 276 (192 residues), 32.2 bits, see alignment E=1.4e-11 PF13437: HlyD_3" amino acids 191 to 284 (94 residues), 36.8 bits, see alignment E=1.1e-12

Best Hits

KEGG orthology group: None (inferred from 86% identity to maq:Maqu_0591)

Predicted SEED Role

"RND efflux membrane fusion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PGU7 at UniProt or InterPro

Protein Sequence (372 amino acids)

>HP15_1119 efflux transporter, RND family, MFP subunit (Marinobacter adhaerens HP15)
MLGPATARTDTHTWILPIGTPAMRCILTLLISLLILSGCQQSSEPPPEAPAHIPWVKTVE
LKEAGPTAQRFSGTLRGRHEVPQAFQIAGRVQQRFIDPGQRVEKGDLLFKLDTRDLAATA
VGAAADLKRAEAALAIATNELQRQQQLVERQFVSEQTLQRLELAEREARSQLETASSRNK
QAQNALGYAELKASNAGVITEVSVEPGQVVGIGQTLAVLAADQLLEVEVFLPEGINPPRR
GYLPLANGKQIAMNLREIAGAADPRSRSWRARYSLEGPYPSSLTLGSVVSVRLAQKQTES
SHRVPLGALDERGQTPQVWLVSDGTVNPLAVEVIDLGKEYAEIKVEINAGTSIVALGTHL
LTRGMAVRELTQ