Protein Info for PGA1_c11200 in Phaeobacter inhibens DSM 17395
Annotation: putative deoxycytidine triphosphate deaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01494, dCTP deaminase [EC: 3.5.4.13] (inferred from 73% identity to dsh:Dshi_1723)Predicted SEED Role
"Deoxycytidine triphosphate deaminase (EC 3.5.4.13)" (EC 3.5.4.13)
MetaCyc Pathways
- superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
- pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.5.4.13
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7DZH0 at UniProt or InterPro
Protein Sequence (369 amino acids)
>PGA1_c11200 putative deoxycytidine triphosphate deaminase (Phaeobacter inhibens DSM 17395) MTSEGQTSSSLTQGVLSDRQIRQMITGAAIAASSPILNDQIQPASLDLRLSDCAYRVRAS FLPGLGRTVAERLEDLTMHRVALTGGAVLEKGCVYVVPLMERIRLPEGMTAAASAKSSIG RLDVMTRVITDQGVEFDRVPDGYDGPLYAEICPQSFSVVVQPGQLLTQIIFRQGRTFLSD ADLRAVHEATPIVSGDPVISDGLGFSVDLRPERGDLVGYRAKHHTGVVDLSKLGHYDPAE YWEEVRTTKGQIILDPGAFYILVSREAIAIPPDYAAEMAPYLAMVGEFRVHYAGFFDPGF GYAAAGGAGSRGVLEVRCHDAPFVLEHGQVVGRLVYEKMSEVPEQLYGVDIASNYQGQGL KLSKHFKTS