Protein Info for HP15_1062 in Marinobacter adhaerens HP15

Annotation: rhomboid family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 transmembrane" amino acids 82 to 100 (19 residues), see Phobius details amino acids 146 to 165 (20 residues), see Phobius details amino acids 177 to 194 (18 residues), see Phobius details amino acids 200 to 216 (17 residues), see Phobius details amino acids 228 to 246 (19 residues), see Phobius details amino acids 258 to 275 (18 residues), see Phobius details PF16733: NRho" amino acids 5 to 51 (47 residues), 39.3 bits, see alignment 5.7e-14 PF01694: Rhomboid" amino acids 134 to 273 (140 residues), 104.2 bits, see alignment E=6.8e-34

Best Hits

Predicted SEED Role

"GlpG protein (membrane protein of glp regulon)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PG84 at UniProt or InterPro

Protein Sequence (281 amino acids)

>HP15_1062 rhomboid family protein (Marinobacter adhaerens HP15)
MDTTVNLAGFSRWLNGQGVTHRITEEGGFQVLWLEDPAHAEPVLSALDRFMAEPEIREAV
DRQNRSPVFVGGRWQPSPRHAPLVLGIIVFAVAMVWLTAMGQNELAASLMVIDPRDYDWS
TMAGRIEALTATLASGQVWRLLTPDFLHFSWTHIIFNSVMLWFLGSQIEWFDGRARLVTL
FVMTSLISNGLQYFVSGPLFGGLSGVVYGILGYCWLSQRSAPRFQFPPALVTFAVAWMVI
GFTPLPEMIGLGRMANEAHLGGFVAGLALAVVLPVKGRRGA