Protein Info for PGA1_c10550 in Phaeobacter inhibens DSM 17395

Annotation: NADH-quinone oxidoreductase subunit N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 479 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 35 to 54 (20 residues), see Phobius details amino acids 73 to 92 (20 residues), see Phobius details amino acids 104 to 123 (20 residues), see Phobius details amino acids 128 to 146 (19 residues), see Phobius details amino acids 158 to 181 (24 residues), see Phobius details amino acids 201 to 223 (23 residues), see Phobius details amino acids 238 to 257 (20 residues), see Phobius details amino acids 269 to 290 (22 residues), see Phobius details amino acids 297 to 319 (23 residues), see Phobius details amino acids 325 to 345 (21 residues), see Phobius details amino acids 369 to 390 (22 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details amino acids 443 to 465 (23 residues), see Phobius details TIGR01770: proton-translocating NADH-quinone oxidoreductase, chain N" amino acids 7 to 450 (444 residues), 468 bits, see alignment E=2e-144 PF00361: Proton_antipo_M" amino acids 123 to 417 (295 residues), 297.8 bits, see alignment E=4.2e-93

Best Hits

Swiss-Prot: 66% identical to NUON_RHOCA: NADH-quinone oxidoreductase subunit N (nuoN) from Rhodobacter capsulatus

KEGG orthology group: K00343, NADH dehydrogenase I subunit N [EC: 1.6.5.3] (inferred from 80% identity to sit:TM1040_0760)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EKP8 at UniProt or InterPro

Protein Sequence (479 amino acids)

>PGA1_c10550 NADH-quinone oxidoreductase subunit N (Phaeobacter inhibens DSM 17395)
MIPADLTVILPEIVLALSAMAALLGAVYTGKDKLAPALIWLMAGLMSALAIWIGTGASGS
REAFNGMFVDDGFARFAKVAILLSASAVLVMGQDYMSRRGMLRFEYPILVALSAVGMMVM
VSAGNLMSLYMGLELQSLALYVVASLRRDSVKSTEAGLKYFVLGALSSGLLLYGASLVYG
FAGTTDFAGIYAVAKHGEVSIGLLFGLVFLISGMAFKVSAVPFHMWTPDVYEGAPTPVTA
FFASAPKIAAMGLFARVMHDAFGHAVQDWSQVIALLSLLSMFVGAVAAIGQRDIKRLMAY
SSIAHMGYALMGLAAGTAYGVQALLVYMAIYVSMNIGTFAFILMMEKDGKPITDIRALNL
YSRREPGKALAMLILLFSLAGVPPMLGFFGKLYVLNAAYQAGLAWLAVAGVIASVIGAFY
YLRIVYYMYFGEEGEELETNRSPILWGFLMASAAVMLLGIINMFGIEGAAASAAATLVN