Protein Info for Psest_0102 in Pseudomonas stutzeri RCH2

Annotation: malonate decarboxylase, alpha subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 PF16957: Mal_decarbox_Al" amino acids 10 to 555 (546 residues), 1003 bits, see alignment E=1.5e-306 TIGR01110: malonate decarboxylase, alpha subunit" amino acids 11 to 555 (545 residues), 1038.5 bits, see alignment E=0

Best Hits

KEGG orthology group: K13929, malonate decarboxylase alpha subunit [EC: 2.3.1.187] (inferred from 99% identity to psa:PST_4120)

Predicted SEED Role

"Malonate decarboxylase alpha subunit" in subsystem Malonate decarboxylase

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.187

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GH10 at UniProt or InterPro

Protein Sequence (555 amino acids)

>Psest_0102 malonate decarboxylase, alpha subunit (Pseudomonas stutzeri RCH2)
MTTTISPPPQWSRRRAEKARRLDQVRSLADGVVLPSERIVEALELLIAPGDRVVLEGNNQ
KQADFLSRSLAKVDPGKLHDLHMIMPSVSRAEHLDLFERQIARKLDFSFAGPQSLRISQL
LEDGLLEVGAIHTYIELYSRLLVDLIPNVALVAGFQADRHGNIYTGPSTEDTPALVEPTA
FSDGIVIFQVNEIVDELPRVDIPASWVDFVVVADKPFYIEPLFTRDPRHIKPVHVLMAMM
AIRGIYEKHNVQSLNHGIGFNTAAIELILPTYGESLGLKGKICRNWTLNPHPTLIPAIET
GWVESVHCFGTELGMENYIAQRPDVFFTGRDGSMRSNRMMCQLAGQYAVDLFIGATLQVD
GDGHSSTVTRGRLAGFGGAPNMGHDPRGRRHPTPAWLDMAMPGGEAPVTMLERGKKLVVQ
MVETFQEGGKPTFVEQLDAVEVAKKSGMPLAPIMIYGDDVTHLLTEEGIAYLYKARSLEE
RQAMIAAVAGVTSIGLRHNPKDTERMRREGLIALPEDLGIRRNDASRELLAAKSIAELVD
WSGGLYNPPAKFRSW