Protein Info for HP15_996 in Marinobacter adhaerens HP15

Annotation: sugar efflux permease, MFS-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 45 to 65 (21 residues), see Phobius details amino acids 76 to 95 (20 residues), see Phobius details amino acids 101 to 125 (25 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 163 to 183 (21 residues), see Phobius details amino acids 207 to 227 (21 residues), see Phobius details amino acids 244 to 264 (21 residues), see Phobius details amino acids 271 to 289 (19 residues), see Phobius details amino acids 295 to 317 (23 residues), see Phobius details amino acids 330 to 351 (22 residues), see Phobius details amino acids 358 to 379 (22 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 324 (310 residues), 85 bits, see alignment E=5.1e-28 PF06779: MFS_4" amino acids 19 to 375 (357 residues), 53.1 bits, see alignment E=3.4e-18

Best Hits

KEGG orthology group: None (inferred from 69% identity to ilo:IL2482)

Predicted SEED Role

"Putative drug efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PFL1 at UniProt or InterPro

Protein Sequence (423 amino acids)

>HP15_996 sugar efflux permease, MFS-like protein (Marinobacter adhaerens HP15)
MKFPSSTSFALLGAALIAISYGLARFAFGLFVPPIRDDLGLAPDVIGVIGALPLISFVFA
TLVAPLSANRLGARNTAMASGIFGVVGLALISQAVGAVSLGVGVVLCGICTGLMMPALTA
AMQALVRRSLHGRVSSVMNAGTSIGVVVAVPTILFLAGAWRYAYASFAVLAVIGVIATWF
FIPSVSRVVPANAAPAQPISADQWWRLLRLSLFAFMMGFVSAAYWIFAPDLVVNLGSMPS
DATAWLWLGVGIAGLGGAVVADLADRNNPPVTQALMLMTLAASLALLAASPDNLMISAFS
ALVFGLAYMSLTGLYLMTGIRLLPGRLSMGPVLPFMAVSLGQAAGSPIVGMLVGKVGYAD
AFAMFCAIGIIVAMLSPLYPRHLEYEPDDETEEDTGLQAAYDYQLQNEEGEPLSPVTGKT
ESY