Protein Info for HP15_986 in Marinobacter adhaerens HP15

Annotation: beta-lactamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 PF00144: Beta-lactamase" amino acids 28 to 384 (357 residues), 231.6 bits, see alignment E=7.3e-73

Best Hits

KEGG orthology group: None (inferred from 75% identity to maq:Maqu_2371)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PFK1 at UniProt or InterPro

Protein Sequence (404 amino acids)

>HP15_986 beta-lactamase (Marinobacter adhaerens HP15)
MTELTQVAGLSTEQLPNIERHLDRCYLQPGKLPGALTLVARRGEIAYVKAQGLMDVERNK
PVRRDTVFRIYSMTKPITSIAMMQLYEQGRFLLDDPVHKYIPAWRHQRIYKSGVYPNFLT
TPASSTMTIRDLFTHMSGLTYGFMQRTNVDAAYRELKLDGSRSMSLEALVDHLAELPLEF
SPGTAWNYSVSTDVLGYLVQLLSGKPFDEYLREHIFEPLDMTDTGFHVRDDQLDRFAACY
QYQAGDQFTLQDDPETSPFRRKPQFMSGGGGLVSTIDDYFHFAQALCQGGEFRGRRIIGR
KTLEFMCRNHLPNNQDLPGLSVGAFSETPFAGTGFGLGFSVKTDVAKSQTNGSVGEYGWG
GLASTNFFVDPVEELVMIFMTQLIPSSTYPIRQELRAIVNGALL