Protein Info for EX31_RS24680 in Rahnella sp. WP5

Annotation: manganese efflux pump MntP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 39 to 59 (21 residues), see Phobius details amino acids 68 to 86 (19 residues), see Phobius details amino acids 106 to 128 (23 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details PF02659: Mntp" amino acids 32 to 182 (151 residues), 176.1 bits, see alignment E=2.2e-56

Best Hits

Swiss-Prot: 77% identical to MNTP_SERP5: Putative manganese efflux pump MntP (mntP) from Serratia proteamaculans (strain 568)

KEGG orthology group: None (inferred from 99% identity to rah:Rahaq_2902)

MetaCyc: 65% identical to Mn2+ exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-487

Predicted SEED Role

"Putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (190 amino acids)

>EX31_RS24680 manganese efflux pump MntP (Rahnella sp. WP5)
MNLSATLILAFGMSMDAFAASIGKGASLHRPCFREAVRTGFIFGVIEAITPLIGWYMGLF
ASQYIMQWSQWVAFTLLFILGARMIIEGLKNKPEDNLTTATRHGFWILAATAIGTSLDAL
AIGVGLAFLEVNIILTALLIGMATMVMSTLGIMVGRFIGPLLGKWAEVLGGAVLIGIGSS
ILLEHLGYLR