Protein Info for EX31_RS23935 in Rahnella sp. WP5
Annotation: ABC transporter substrate-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 73% identical to YEHZ_ECOLI: Glycine betaine-binding protein YehZ (yehZ) from Escherichia coli (strain K12)
KEGG orthology group: K05845, osmoprotectant transport system substrate-binding protein (inferred from 99% identity to rah:Rahaq_3049)MetaCyc: 73% identical to glycine betaine ABC transporter periplasmic binding protein OsmF (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-283
Predicted SEED Role
"Osmoprotectant ABC transporter binding protein YehZ"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (312 amino acids)
>EX31_RS23935 ABC transporter substrate-binding protein (Rahnella sp. WP5) MTVTTGRVRGFSVAALALASVVSFSAQAADDAVRVGSKIDTEGSLLGNIIIQVLEANGIH TTNKLQLGTTKVVRGAITAGEIDIYPEYTGNGAFFFSDDKDPAWKNAQAGFDKVKKLDYD QNKVVWLDPSPANNTWTIAVRQDVASAHNLKSLGDLGKYISSGGDFKLAASAEFIERPDA LPAFENAYGFKLNQAQLLSLAGGDTAVTIKAAAEQTSGVNAAMAYGTDGPVAALGLQTLE DPKGVQPIYAPAPVIREAALKAHPNIPELLKPVFASLDTKTLQGLNAKIAVDGQDAKKVA AKYLQEKGFVKK