Protein Info for EX31_RS22950 in Rahnella sp. WP5

Annotation: ShlB/FhaC/HecB family hemolysin secretion/activation protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF08479: POTRA_2" amino acids 69 to 142 (74 residues), 65.3 bits, see alignment E=3.6e-22 PF03865: ShlB" amino acids 204 to 511 (308 residues), 106.6 bits, see alignment E=1.8e-34

Best Hits

KEGG orthology group: None (inferred from 99% identity to rah:Rahaq_3242)

Predicted SEED Role

"Hemolysin activation/secretion protein associated with VreARI signalling system"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (552 amino acids)

>EX31_RS22950 ShlB/FhaC/HecB family hemolysin secretion/activation protein (Rahnella sp. WP5)
MRIRLTPIALALLTLTASTARAEIVPDAGQSIREIQTKPPVLPPRQTLELNLPDTPDTHP
TARGPTMQVAQFRLTGNQAISSADLLPLLADLQNRTVSFGELQAAAGRITLFYRQKHYPL
ARAYLPAQDVENGVVTIAVLEGHFGEVKLNNASRISDGTLAAPLRALKNGEAVRAGPLER
SLLLLQEIPGVEVRSTLKPGTAVGASDLVVDARSAPMVSGQVDLDNYGNRFTGEYRLGST
LNLASPSGMGDQASMRIMGSDEDQHYFRAAYQLPIGPWATQVGVAYSYMNYQLARNFDNL
DASGNAKIASVFVQQPLIRLRDFSLTAQLQFDDKRLRDDIDLYDYKSHKQSHVVTASLNG
NSRDNFLGGGSNAFSLAWSQGNLTLDNPQDKVLDDLTARTRGTFQKINPGIVRLQRLTDR
ISLYGQFQGQWTDGNLDSSEKISLGGAYGVRAYPEGEAQGDQGYVTSAELRYALTEMVQL
FTFVDHGEVRLNKDTWADGENHRSLSATGVGSTLSAGNWHLMAVAAWKLGNADAQSDTDR
TPRVWAQASRTF