Protein Info for EX31_RS22420 in Rahnella sp. WP5

Annotation: adenine deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 595 PF01979: Amidohydro_1" amino acids 75 to 353 (279 residues), 89.4 bits, see alignment E=4.4e-29 PF13382: Adenine_deam_C" amino acids 415 to 579 (165 residues), 131.2 bits, see alignment E=3.8e-42

Best Hits

Swiss-Prot: 76% identical to ADEC_SERP5: Adenine deaminase (ade) from Serratia proteamaculans (strain 568)

KEGG orthology group: K01486, adenine deaminase [EC: 3.5.4.2] (inferred from 100% identity to rah:Rahaq_3330)

Predicted SEED Role

"Adenine deaminase (EC 3.5.4.2)" in subsystem Purine conversions (EC 3.5.4.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (595 amino acids)

>EX31_RS22420 adenine deaminase (Rahnella sp. WP5)
MTDGITSQPLRQRAINAALGNIPFDRLLINARVIDMVTGEIREADVGITGNMIASVHSRG
KFTQTENVDDLSGNYLSPGLIDTHVHIESSHLPPEKYAEIVVAQGTTTVFWDPHELANVL
GVAGVQYAIQSSRNLPLRVICAAPSSVPSTPGLEMSGADFTGQEMQTMLSWPEIAGVAEV
MDMHGVLNGSGRMLEILEAGLNSGKLIEGHARGLKDEQLQAYLAAGVTSDHELTSADDAL
EKLRAGLTLQIRGSHPYLLPDIAAALLALPHLSSQITLCTDDVPPDHLLEKGGLIALIKL
LISYGLRAEDVLRMATLNAAIRMQRSDLGLIAAGRTADLIAFDSLENLLPRAVYVGGTCV
AQQGKLLFTPAAASGVVPPRDTMRLTPLNAADFRLKIPGLNNGKARLRNIKGARFTQWSE
VTVNVRDGAVQIPDGFSLIWVQHRHGRHDATPKMALLEGWGALRGAIATSYSHDAHNLVI
IGRDPVDMMIAANQLIASGGGMALSQHGKLLANIDMPIAGMLSDLPATELAKQFKNLRDL
SAQVADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGGSREIVNPVLEIWPEEI