Protein Info for EX31_RS22335 in Rahnella sp. WP5

Annotation: MGMT family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 102 TIGR00589: methylated-DNA--[protein]-cysteine S-methyltransferase" amino acids 6 to 79 (74 residues), 53.9 bits, see alignment E=7.3e-19 PF01035: DNA_binding_1" amino acids 6 to 86 (81 residues), 92.4 bits, see alignment E=6.7e-31

Best Hits

Swiss-Prot: 54% identical to ATL_VIBPQ: DNA base-flipping protein (A79_1377) from Vibrio parahaemolyticus serotype O3:K6 (strain AQ3810)

KEGG orthology group: K07443, methylated-DNA-protein-cysteine methyltransferase related protein (inferred from 99% identity to rah:Rahaq_3332)

Predicted SEED Role

"methylated-DNA--protein-cysteine methyltransferase-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (102 amino acids)

>EX31_RS22335 MGMT family protein (Rahnella sp. WP5)
MSEPDNFRQRVFQIIAAIPVGQVTTYGNVAQLAGSPRAARQVGGVLKKLPEGSTLPWHRV
INRHGEISLQGEDFKRQRQALLAEGITFKKGKIDLEKYGWKW