Protein Info for EX31_RS22030 in Rahnella sp. WP5

Annotation: exonuclease subunit SbcC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1082 TIGR00618: exonuclease SbcC" amino acids 1 to 1073 (1073 residues), 603.7 bits, see alignment E=3.6e-185 PF13476: AAA_23" amino acids 5 to 265 (261 residues), 66.3 bits, see alignment E=9.1e-22 PF13555: AAA_29" amino acids 26 to 58 (33 residues), 27.7 bits, see alignment (E = 2.8e-10) PF13558: SbcC_Walker_B" amino acids 967 to 1037 (71 residues), 47.6 bits, see alignment 2.4e-16

Best Hits

KEGG orthology group: K03546, exonuclease SbcC (inferred from 99% identity to rah:Rahaq_3397)

Predicted SEED Role

"Exonuclease SbcC" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1082 amino acids)

>EX31_RS22030 exonuclease subunit SbcC (Rahnella sp. WP5)
MKILSLRLKNLNSLEGEWKIDFTAEPFASNGLFAITGPTGAGKTTLLDAICLALYHQTPR
LNITPSQNELMTRHTAESLAEVEFEVKGVGYRAFWSQRRAKNSPDGNLQAPKVELALLAD
GKILADKVRDKLDAIATLTGLDFGRFTKSMMLSQGQFAAFLNADANDRAELLEELTGTEI
YGLLSQRVFEQHKEARIALDGLHQRMAGIELLSEEQRQTLEAQRAELNTQEITLSQQAQQ
RQQDLNWLQQWQQVQQKQQQSQQQLTAAEQENLTAAPQLQQLARSEPAEKLRPLLNDRQR
CRDDAQRLQQLLIQLTQQQEQQIAQMTPLSLAVEQAHTARQKQAEEQRQMQTLIEEKILP
LDSEIAQWRKSLVETQQAVSESQKQAGEHSATLQQITAERQKLDEESRQHHTRQAALTEA
LNVAQQRQAELEKQYPQVVLQKRQTELMQLRPVRQQLFSLAQIFPQLNQRVQQQHKDFAQ
YQMLLAEEELRLGAIRLQCQKQLEHLNDVKALHKQEMLIVSLEAERANLQSGKACPLCGS
TSHPAIEHYQQVKPSETAQRVEKMQLEFDAAKASGIELAAKIKGLKEQQTRLQTQLEQDQ
QQLNAHTLNWQQLSAPLNLTFTLHDTADITQWLTARDEEEQQSQARLSQHEQLARALQQA
KDALNDALNAQQKVQQQSALLTERVTRLEEMQAKSQQDLVRLQKQLAEGEKSLSELNARR
LELFGERQVAQVREHLHQQQQATEQALSDVQTALHKAQEQRDQLAGQLASTQQQQLQTAA
QLTQVEQAWQQALSASGFADEAAVKLALLDDALRQQLQQRKEHLQQQLAQAQALLADARQ
QLEKHQLARPAHLSETDSDLNALTVQQAELAQQLKVLQQRLGEVKNQLESDKQRHHGQQT
LIAQIAQAQRTCDDWGYLNQMIGSSDGAKFRKFAQGLTLDHLVYLANRQLEKLHGRYLLQ
RKTSDALELQVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSDKTRIDSLFLDEG
FGTLDADTLDTALDALDSLNASGKTIGVISHVEAMKDRIPVQIKVTKVNGLGISRLSSEF
KV