Protein Info for EX31_RS21875 in Rahnella sp. WP5

Annotation: PTS transporter subunit EIIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 122 to 143 (22 residues), see Phobius details amino acids 159 to 181 (23 residues), see Phobius details amino acids 191 to 212 (22 residues), see Phobius details amino acids 218 to 236 (19 residues), see Phobius details amino acids 249 to 271 (23 residues), see Phobius details amino acids 291 to 310 (20 residues), see Phobius details amino acids 330 to 351 (22 residues), see Phobius details amino acids 363 to 382 (20 residues), see Phobius details amino acids 388 to 418 (31 residues), see Phobius details amino acids 429 to 451 (23 residues), see Phobius details PF00367: PTS_EIIB" amino acids 10 to 41 (32 residues), 45.3 bits, see alignment (E = 4.5e-16) PF02378: PTS_EIIC" amino acids 121 to 395 (275 residues), 132.9 bits, see alignment E=1.4e-42

Best Hits

KEGG orthology group: K02809, PTS system, sucrose-specific IIB component [EC: 2.7.1.69] K02810, PTS system, sucrose-specific IIC component (inferred from 100% identity to rah:Rahaq_3426)

Predicted SEED Role

"PTS system, N-acetylmuramic acid-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylmuramic acid-specific IIC component" in subsystem Sialic Acid Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>EX31_RS21875 PTS transporter subunit EIIC (Rahnella sp. WP5)
MDKTQRLASQILQGVGGERNISKLENCMTRVRVEVHDDNRLDLTSLKTLEGIKGYLKQGD
QHQFIVGPGAAAKVVDAMRLLLNPAGTVSSPGDESEIARNKASAKTKYSAPMSGALRKLA
DVFIPLIPAFIASGLIMGIINLLKRPDIAGSIALDYPNVLGLLAIFGGAVFAIMNILVGV
NAARVFGGSQAMGGVMAGILSSPALAQITLFGEALQPGRGGVIAVLLVVALMCWLEKRLR
QWLPESVELILNPLITTLITATLAIVILQPIGGYISDGIAHGVNIAIDKGGLLVGAVLAG
TFLPLVLSGLHQGLVPIHVELIQAHGSNPLLPILAMAGVGQVGAAIAVYIKTRNPRLKKV
IKGALPVGILGIGEPLIFGVTLPLGRPFIGACLGGAVGGALICYWKVATVITFGISGLPL
ALTIISGKVMLYLTGLVITVLAGFIFTWLMGFNDPEE