Protein Info for EX31_RS20730 in Rahnella sp. WP5

Annotation: exodeoxyribonuclease V subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 684 TIGR01447: exodeoxyribonuclease V, alpha subunit" amino acids 13 to 682 (670 residues), 585.6 bits, see alignment E=6.1e-180 PF21185: RecD_N" amino acids 15 to 130 (116 residues), 45.4 bits, see alignment E=3.5e-15 PF13245: AAA_19" amino acids 182 to 340 (159 residues), 111.5 bits, see alignment E=1.6e-35 PF13604: AAA_30" amino acids 185 to 357 (173 residues), 92.7 bits, see alignment E=1.2e-29 PF13086: AAA_11" amino acids 189 to 274 (86 residues), 28.1 bits, see alignment E=8.1e-10 PF13401: AAA_22" amino acids 193 to 332 (140 residues), 28.4 bits, see alignment E=8.5e-10 PF05127: Helicase_RecD" amino acids 196 to 321 (126 residues), 30.5 bits, see alignment E=1.4e-10 PF13538: UvrD_C_2" amino acids 610 to 653 (44 residues), 43.9 bits, see alignment 7.9e-15

Best Hits

KEGG orthology group: K03581, exodeoxyribonuclease V alpha subunit [EC: 3.1.11.5] (inferred from 99% identity to rah:Rahaq_0995)

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (684 amino acids)

>EX31_RS20730 exodeoxyribonuclease V subunit alpha (Rahnella sp. WP5)
MKINSREDIAQLLASWVECGWLRELDRALVTFLAKEAPDAHPLLLLATALTSYQLGRGHV
CLDLQATLDDSAFSLSLPPEGDHADGAVIRPAAVLDDLSLQEWLAALVHPTLVGHHEGNS
PLVLTGQRLYLRRYWQYEQNVRAAIEQRLARSALHTLPVESLRAPLTALFPADAKSDIAN
WQKLACALAAGSAFSIITGGPGTGKTTTVVRLLALLQTLALEENGQPLRIRLAAPTGKAA
ARLNESIAGAVSKLDLSALGNGNAVRESINTDVVTLHRLLGSRPDTRHFRHHPGNPLMLD
VLVVDEASMVDLEMMAALLAALPEQARLILLGDKDQLASVEAGALLSELCQRANGGHYLP
HTRDWLQSVTGEQVPDSLVDPQGTAMDQAVVMLRHSYRFDAQSGIGQLAEAVNDGDVKAL
KQVWKHGYADLAQLTLSADDDAELRDWVVKGGAKQFPTAARREGVEPPVGYQHYLNVMIQ
ARPADNEPPEAFNRWAARVLLAYSQFQLLCALRGGRWGVEELNQRIADILRKEGLLKASI
GWYPGRPVLVTRNDYSQRLMNGDIGITLEIPHRLADGTVVPTLRVAFLAGDGTQDIRWVM
PGRLQAVETVFAMTVHKSQGSEFTHTALLLPENLSPILTRELIYTGITRARHWFSLGCVG
GMNAVLPDAVKRRVLRASGLIESA