Protein Info for EX31_RS20465 in Rahnella sp. WP5

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 113 to 113 (1 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 149 to 171 (23 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 242 to 265 (24 residues), see Phobius details amino acids 279 to 302 (24 residues), see Phobius details amino acids 313 to 334 (22 residues), see Phobius details amino acids 340 to 364 (25 residues), see Phobius details amino acids 379 to 398 (20 residues), see Phobius details amino acids 404 to 426 (23 residues), see Phobius details PF07690: MFS_1" amino acids 30 to 356 (327 residues), 171.8 bits, see alignment E=1e-54 amino acids 316 to 433 (118 residues), 35.2 bits, see alignment E=3.6e-13

Best Hits

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 100% identity to rah:Rahaq_1053)

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (437 amino acids)

>EX31_RS20465 MFS transporter (Rahnella sp. WP5)
MTIQINTGTAAVAGRRKIKALRWWMLALFLLGVTVNYVTRNSLGLLAAELKTSLNMTTEQ
YSYIVAAFQAAYTIFQPLCGWLIDVIGLKLGFLICASIWAVVCMLHAGAGSWIQLAVLRF
FMGSAEAAATPANAKAISDWFPRKERPVAAGWAGVGFSIGAMLAPPIILVAHVSFGWRGA
FLFCGVLSMLWVLLWWKFYHSPETHPNLSKDELALIRSDNEPQQTRLPFIKSLKIVCKNK
KFYGIAIPAFLAEPAWAVFSFWVPLYLANERGMDLKHIVMFAWLPFLAADLGSIASGYLT
TLYRKVFGCTRINSIVASSVTGAFMMLSLALVALTQSPYAAIALISIGGFGHQVISCMLS
AVVVETFDKSQVATVNGMRGSSAWIASFLFSLLIGAVADKMGFNPLFIAMGFFDLIGAVF
LVALIAERRNPAKRESL