Protein Info for EX31_RS18860 in Rahnella sp. WP5

Annotation: kdo(2)-lipid A phosphoethanolamine 7''-transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 558 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 63 (22 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 119 to 137 (19 residues), see Phobius details amino acids 153 to 174 (22 residues), see Phobius details PF08019: EptA_B_N" amino acids 54 to 168 (115 residues), 38.7 bits, see alignment E=9.2e-14 PF00884: Sulfatase" amino acids 246 to 534 (289 residues), 192 bits, see alignment E=1.6e-60

Best Hits

KEGG orthology group: None (inferred from 98% identity to rah:Rahaq_1381)

Predicted SEED Role

"Phosphoethanolamine transferase specific for the outer Kdo residue of lipopolysaccharide" in subsystem Lipid A modifications

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (558 amino acids)

>EX31_RS18860 kdo(2)-lipid A phosphoethanolamine 7''-transferase (Rahnella sp. WP5)
MHKIRTLSQQSISLFIALYLGLLLNLPIFIRRYQQLHYDNALSIAVEMVACFALVYFLCM
LLSYTGKTVFRVLMTAIVISSAAASYYMILFNVDIGYGILAAALASDSIDLSKESIGTHF
LAWTVLVSLLPVLLLWLSKMPGAALKQTTFKKLAVRTLLLAASGLLCYMPLQLMGKVQDR
HDIVNNRMMASYGGVVAGTYSPSNWLSALGLYTYSSYSQAEDTKNLYDPAKHFTYTAPAD
AKDMYVVFVIGESARRDHMGLYGYDRDNTPNLDKEKNLVALQGYSCDTATKLSLRCMFVR
EGGASEEPQRTLKEMNVFSVLKSNGWSSELYSMQSEAWFYNKTRADDYSLRENIASEKRN
AGKPVDDMLLIDEMKDSMNNHPKGKHLIILHTKGSHYLYSDRYPRSFAKYKPECMGIDNS
CSTGEMINAYDNSLLYTDYFLSQVFDQLRDKNAIVFYASDHGESISKSMHFHGTPRDHAP
IEQRKVPIMVWASDKFLANDQNKASFQQLQKMAATKTPAFHEKLYDTILGCIGYTSPNGG
IVEQHNWCHVPDQAAATK