Protein Info for EX31_RS18550 in Rahnella sp. WP5

Annotation: leucyl/phenylalanyl-tRNA--protein transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 PF03588: Leu_Phe_trans" amino acids 37 to 203 (167 residues), 241.4 bits, see alignment E=2.1e-76 TIGR00667: leucyl/phenylalanyl-tRNA--protein transferase" amino acids 39 to 225 (187 residues), 251.5 bits, see alignment E=2.2e-79

Best Hits

Swiss-Prot: 71% identical to LFTR_SERP5: Leucyl/phenylalanyl-tRNA--protein transferase (aat) from Serratia proteamaculans (strain 568)

KEGG orthology group: K00684, leucyl/phenylalanyl-tRNA--protein transferase [EC: 2.3.2.6] (inferred from 100% identity to rah:Rahaq_1445)

MetaCyc: 62% identical to leucyl/phenylalanyl-tRNA--protein transferase (Escherichia coli K-12 substr. MG1655)
Leucyltransferase. [EC: 2.3.2.6]; 2.3.2.6 [EC: 2.3.2.6]; 2.3.2.6 [EC: 2.3.2.6]; 2.3.2.6 [EC: 2.3.2.6]

Predicted SEED Role

"Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6)" in subsystem Protein degradation (EC 2.3.2.6)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (244 amino acids)

>EX31_RS18550 leucyl/phenylalanyl-tRNA--protein transferase (Rahnella sp. WP5)
MRLVKLEANSLNFPAPETALQEPNGLLAIGGDLTAPRLLSAYQHGIFPWFEPGEMILWWS
PDPRAILVPGERHASRSLKRFMRKMPFRFTLNQQFEQVIHACAMQREDGTWIGPLVQRGY
QELHEAGRAHSVEVWEGDELVGGLYGVSVGGLFCGESMFSRRENASKCALMLFCQHFSRN
GGELIDCQVLNPHTASLGAREIPRRQFLQQLSALSQRALAPDCWLPQDLSPHDEDLPVFP
KDRE