Protein Info for EX31_RS18545 in Rahnella sp. WP5

Annotation: cysteine/glutathione ABC transporter ATP-binding protein/permease CydC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 573 transmembrane" amino acids 18 to 66 (49 residues), see Phobius details amino acids 134 to 157 (24 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details amino acids 243 to 267 (25 residues), see Phobius details amino acids 278 to 301 (24 residues), see Phobius details TIGR02868: thiol reductant ABC exporter, CydC subunit" amino acids 6 to 533 (528 residues), 544.4 bits, see alignment E=1.4e-167 PF00664: ABC_membrane" amino acids 39 to 286 (248 residues), 44.7 bits, see alignment E=2.2e-15 PF00005: ABC_tran" amino acids 356 to 502 (147 residues), 110 bits, see alignment E=2.3e-35

Best Hits

Swiss-Prot: 66% identical to CYDC_ECOLI: ATP-binding/permease protein CydC (cydC) from Escherichia coli (strain K12)

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 99% identity to rah:Rahaq_1446)

MetaCyc: 66% identical to glutathione/L-cysteine ABC exporter subunit CydC (Escherichia coli K-12 substr. MG1655)
7.4.2.-; 3.6.3.M9 [EC: 3.6.3.M9]

Predicted SEED Role

"Transport ATP-binding protein CydC" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.M9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (573 amino acids)

>EX31_RS18545 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC (Rahnella sp. WP5)
MKTLLPYLALYRRHGFRLSLGVILAIVTLLASIGLLTLSGWFLAASAVAGVAGLYSFNYM
LPAAGVRGAAIFRTAGRYAERLVSHDATFRVLAHLRVFTFTKILPLSPGGIAHFRQADLL
NRLVADVDTLDHLYLRVISPLVSALVVIILVTFGLSFLDVKLALTLGAIMLVLMLLLPVI
FYRAGKPAGRELTALRSNYRMQLTSWLQGQSELVVFGAQSRFRQQLNDIEQRWMLRQQQQ
AKLTGLSQAMVIAAAGLTVTLMLWLAAGGINQFPQPGALIALFVFTPLAAFEALGPVAAA
FQHLGQVIASAQRVSQIIDQPAEVTFPSQGPLAGERVSLSLKNVNFTYPGQPLPVLKNIN
LDVRAGEHIALLGQTGCGKSTLLQLLTRAWDISNGALEINGHPVADYDEATLRKMITVVS
QRAHVFNTTLRENLRMASPQSTDEQIADALKQVDLHVLLENEGLNAWLGEGGRQLSGGEQ
RRIGLARALLHDAPLWLLDEPTEGLDAETEQHILALLHKHCQNKTLLLVTHRLHGLEALD
RICVMEEGQIVEQGDHQTLAAAQSRYARFLARA