Protein Info for EX31_RS18490 in Rahnella sp. WP5

Annotation: dimethyl sulfoxide reductase anchor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 45 to 67 (23 residues), see Phobius details amino acids 87 to 104 (18 residues), see Phobius details amino acids 116 to 138 (23 residues), see Phobius details amino acids 150 to 169 (20 residues), see Phobius details amino acids 181 to 203 (23 residues), see Phobius details amino acids 225 to 245 (21 residues), see Phobius details amino acids 252 to 275 (24 residues), see Phobius details PF04976: DmsC" amino acids 1 to 275 (275 residues), 345.8 bits, see alignment E=9.6e-108

Best Hits

Swiss-Prot: 57% identical to YNFH_ECOLI: Anaerobic dimethyl sulfoxide reductase chain YnfH (ynfH) from Escherichia coli (strain K12)

KEGG orthology group: K07308, anaerobic dimethyl sulfoxide reductase subunit C (DMSO reductase anchor subunit) (inferred from 100% identity to rah:Rahaq_1458)

MetaCyc: 57% identical to putative menaquinol dehydrogenase (Escherichia coli K-12 substr. MG1655)
Selenate reductase. [EC: 1.97.1.9]

Predicted SEED Role

"Anaerobic dimethyl sulfoxide reductase chain C (EC 1.8.5.3)" (EC 1.8.5.3)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.8.5.3

Use Curated BLAST to search for 1.8.5.3 or 1.97.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>EX31_RS18490 dimethyl sulfoxide reductase anchor subunit (Rahnella sp. WP5)
MGNGWHEWPLMVFTVLGQCVVGAFIVLAIALLTQRSREEYRQIHLSMFFLWVLMAIAFIA
SVLHLGSPLRAFNSLNRLGASPLSNEIGSGSLFFALGGIYWLLAMINKMPRVLAKIWLIV
TMLAGVGFVFAMCRVYAINTVPTWDNAYTAFHFGLTVLIGGPVLGYLLLRGANINGCALR
LLPVISFVSLVVSMAVVVMQSASLAGISSSVQAASALIPQYGVLSVWRLVLVVLGLGCWF
CPLILRKRPALASMILAFVLVFAGELIGRAIFYGLHMTVGMAVGG