Protein Info for EX31_RS17745 in Rahnella sp. WP5

Annotation: shikimate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 transmembrane" amino acids 25 to 49 (25 residues), see Phobius details amino acids 61 to 84 (24 residues), see Phobius details amino acids 97 to 123 (27 residues), see Phobius details amino acids 129 to 151 (23 residues), see Phobius details amino acids 163 to 185 (23 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 257 to 276 (20 residues), see Phobius details amino acids 289 to 310 (22 residues), see Phobius details amino acids 319 to 337 (19 residues), see Phobius details amino acids 343 to 364 (22 residues), see Phobius details amino acids 384 to 406 (23 residues), see Phobius details amino acids 415 to 433 (19 residues), see Phobius details TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 30 to 426 (397 residues), 486.1 bits, see alignment E=4.3e-150 PF00083: Sugar_tr" amino acids 31 to 434 (404 residues), 78.9 bits, see alignment E=3.8e-26 PF07690: MFS_1" amino acids 33 to 383 (351 residues), 90.2 bits, see alignment E=1.3e-29 amino acids 261 to 437 (177 residues), 45.3 bits, see alignment E=5.9e-16

Best Hits

Swiss-Prot: 83% identical to SHIA_ECOLI: Shikimate transporter (shiA) from Escherichia coli (strain K12)

KEGG orthology group: K08172, MFS transporter, MHS family, shikimate and dehydroshikimate transport protein (inferred from 100% identity to rah:Rahaq_1609)

MetaCyc: 83% identical to shikimate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-27

Predicted SEED Role

"Shikimate transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (439 amino acids)

>EX31_RS17745 shikimate transporter (Rahnella sp. WP5)
MDSMLTAPHPDEEIPSYHRARRAAWGSFVGAVVDWFDFLLYGITAALVFNSEFFPQIDPA
MGTLAAFATFGVGFLFRPLGGIVFGHFGDRLGRKRMLMMTVWIMGIATACIGILPSFATI
GWWAPALLVTLRAIQGFAVGGEWGGAALLAVESAPSGKKAFYSSGIQMGYGVGLLLATGL
VSLISSLTTDAQFLSWGWRLPFLFSVVLVLGALWVRNGMEESVEFERAQEKLPKAAKKRL
PVFEALLRHPGAFLKIILLRLCELLTMYIVTAFALNYSTHNLGMSRELFLNIGLLVGGIS
CLTIPLFAWLADRFGRRRIYITGALVGAMSAFPFFMALEARSIAGVVIFSLLLANIAHDM
VVCVQQPMFTEMFGAGYRYSGAGVGYQVASVVGGGFTPFIAAALLNFSGGEWHSVAIYLM
AGCLLSALTAMFMKTPAPR