Protein Info for EX31_RS15990 in Rahnella sp. WP5

Annotation: Trk system potassium transporter TrkA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF02254: TrkA_N" amino acids 3 to 124 (122 residues), 100.3 bits, see alignment E=5.9e-32 amino acids 235 to 350 (116 residues), 93.5 bits, see alignment E=7.5e-30 PF02080: TrkA_C" amino acids 157 to 225 (69 residues), 45.5 bits, see alignment E=3.6e-15 amino acids 391 to 449 (59 residues), 38 bits, see alignment E=8.2e-13 PF01488: Shikimate_DH" amino acids 232 to 327 (96 residues), 24.6 bits, see alignment E=1.6e-08 PF13241: NAD_binding_7" amino acids 233 to 319 (87 residues), 24.8 bits, see alignment E=1.8e-08

Best Hits

Swiss-Prot: 87% identical to TRKA_SALTY: Trk system potassium uptake protein TrkA (trkA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03499, trk system potassium uptake protein TrkA (inferred from 100% identity to rah:Rahaq_0373)

Predicted SEED Role

"Trk system potassium uptake protein TrkA" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase or Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (458 amino acids)

>EX31_RS15990 Trk system potassium transporter TrkA (Rahnella sp. WP5)
MKIIILGAGQVGGTLAENLVGENNDITVVDTNTIRLRQLQDKFDLRVVQGHGSHPRVLRE
AGAEDADMLVAVTNSDETNMVACQIAYSLFNTPNRIARIRSTEYIRESEKLFHPEAVPID
HLISPEQLVTDYIYKLIEYPGALQVVNFAEGKVSIAAVKAYYGGPLVGNALSSMREHMPH
IETRVAAIFRQDRPIRPQGSTIIEAGDEVFFVAASQHIRAVMSELQRLEKPYKRIMIVGG
GNVGAGLAQRLEKNYSVKLIERDQQRAAELAEILQDTIVFYGDASDQELLAEEHIEQVDV
FIAITNDDEANIMSAMLAKRMGAKKAMVLIQRSAYVDLVQGSVIDIAISPQQATISALLG
HVRKADIVSVSSLRRGVAEAIEAIAHGDETTSKVVGRTVEQIKLPPGTTIGAIVRGNEVI
IANGTSRIQQGDHVVMFITDKKFVRDVERLFQPSPFFL