Protein Info for EX31_RS15835 in Rahnella sp. WP5

Annotation: uracil-xanthine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 transmembrane" amino acids 37 to 63 (27 residues), see Phobius details amino acids 70 to 88 (19 residues), see Phobius details amino acids 98 to 117 (20 residues), see Phobius details amino acids 129 to 150 (22 residues), see Phobius details amino acids 159 to 183 (25 residues), see Phobius details amino acids 195 to 213 (19 residues), see Phobius details amino acids 220 to 241 (22 residues), see Phobius details amino acids 261 to 281 (21 residues), see Phobius details amino acids 351 to 373 (23 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details amino acids 409 to 430 (22 residues), see Phobius details amino acids 439 to 459 (21 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 30 to 458 (429 residues), 465.2 bits, see alignment E=2e-143 PF00860: Xan_ur_permease" amino acids 35 to 427 (393 residues), 367.5 bits, see alignment E=3.6e-114 TIGR03173: xanthine permease" amino acids 40 to 460 (421 residues), 424.1 bits, see alignment E=5e-131

Best Hits

Swiss-Prot: 86% identical to XANP_ECOLI: Xanthine permease XanP (xanP) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_4376)

MetaCyc: 86% identical to xanthine:H+ symporter XanP (Escherichia coli K-12 substr. MG1655)
RXN-5076

Predicted SEED Role

"Xanthine-uracil permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (463 amino acids)

>EX31_RS15835 uracil-xanthine permease (Rahnella sp. WP5)
MSSQTAEQETQQPDLSRQQKSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQ
ALGLPAQDTQHIISMSLFASGLASILQIKTWGPVGSGLLSIQGTSFNFVAPLIMGGMALK
NGGADVPTMMAALFGTLMLASCTEIILSRFLHLARRIITPLVSGIVVMIIGLSLIQVGLT
SIGGGYAAMSDHTFGAPKNLLLAAVVLVVIVLLNRQRNPYLRVASLVIAMAVGYLVAWMT
GMLPTVAPAAQSNWITLPTPLYYGLGFDWNLLIPLMLIFMVTSLETIGDITATSDVSEQP
VSGPLYMKRIKGGVLANGLNSMLSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALML
IILGLFPAVAGFVQHIPEPVLGGATIVMFGTIAASGVRIVSRERLNRRAIMIMALSLAVG
MGVSQQPLILQFAPDWLKTLLSSGIAAGGITAIVLNLVFPHEK