Protein Info for EX31_RS15825 in Rahnella sp. WP5

Annotation: PTS sugar transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 34 to 53 (20 residues), see Phobius details amino acids 79 to 102 (24 residues), see Phobius details amino acids 110 to 129 (20 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 212 to 236 (25 residues), see Phobius details amino acids 239 to 260 (22 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 394 to 413 (20 residues), see Phobius details TIGR00410: PTS system, lactose/cellobiose family IIC component" amino acids 16 to 425 (410 residues), 356.9 bits, see alignment E=8.1e-111 PF02378: PTS_EIIC" amino acids 32 to 351 (320 residues), 192.9 bits, see alignment E=3.9e-61

Best Hits

KEGG orthology group: K02761, PTS system, cellobiose-specific IIC component (inferred from 100% identity to rah:Rahaq_4374)

Predicted SEED Role

"PTS system, cellobiose-specific IIC component (EC 2.7.1.69)" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>EX31_RS15825 PTS sugar transporter subunit IIC (Rahnella sp. WP5)
MSISQSLFTFIEQKISPFAARLSSQRHVMAVRDGFISAMPFMIVGSFLLVFVHPPFSPES
SWGFARSWLALSAKYEVQILTPFNMTMGIMSIYISASIAYNLARSYKLDPFMTAMLALMS
FLLVAAPQIDEKMSTAALGGVGIFTAILVAIYVTELTRLLKKYNIGIRLPEQVPSNIKHS
FDLLIPIVAVVITLFPLSLLVQSGFDMLLPQAIMALFEPLISAADSLPAVLLAVLICHLL
WFAGIHGSAIVSGMLQAFWLTNLGLNQTDLAAGLPMTHIMTEAFWNFLIVIGGSGATMGL
VLLFCRSKSAHLRTMGKLSLVPSCFNINEPVIFGTPIVMNPVFFIPFLLAPMVNAVIAYL
AVSTDLLPHMISLVPWTSPAPIGAAWAMGWDFKVSVLVILLMALSMVIYYPFFKVYEKQL
LTQEKAAEAEQVFTEKADAAQ