Protein Info for EX31_RS15550 in Rahnella sp. WP5

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 transmembrane" amino acids 25 to 52 (28 residues), see Phobius details amino acids 64 to 85 (22 residues), see Phobius details amino acids 90 to 112 (23 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 197 to 219 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 27 to 119 (93 residues), 87.5 bits, see alignment E=3.5e-29 PF00528: BPD_transp_1" amino acids 43 to 226 (184 residues), 74.1 bits, see alignment E=6.4e-25

Best Hits

Swiss-Prot: 33% identical to YECS_ECOLI: L-cystine transport system permease protein YecS (yecS) from Escherichia coli (strain K12)

KEGG orthology group: K10040, putative glutamine transport system permease protein (inferred from 100% identity to rah:Rahaq_2717)

MetaCyc: 33% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltK (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (249 amino acids)

>EX31_RS15550 amino acid ABC transporter permease (Rahnella sp. WP5)
MLEMFTILHDNGMLFLMGQYPQGPLGGILCTLLISLLAVLFALPVGILLGLARLSPFRWL
SWPAACWVYGLRGIPLLMVVFWTYFCVPLLIGHNISGFSTMLCTLVIYESAYIAEIVRGG
IQALPGGQYEAARALGMSYFKTLRLIILPQALYNTLPSLVSQLVSIIKDSTLGYVINVPE
LTFAANQVNNQLLTKPFQVFAIVAIGYYIICFSLTWLANKLEARITRKRQNRMPEAEKMT
KAPLLKTQS