Protein Info for EX31_RS12670 in Rahnella sp. WP5

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 47 to 69 (23 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 102 to 122 (21 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 165 to 185 (21 residues), see Phobius details amino acids 235 to 255 (21 residues), see Phobius details amino acids 266 to 286 (21 residues), see Phobius details amino acids 304 to 322 (19 residues), see Phobius details amino acids 328 to 349 (22 residues), see Phobius details amino acids 361 to 384 (24 residues), see Phobius details amino acids 390 to 412 (23 residues), see Phobius details PF07690: MFS_1" amino acids 16 to 293 (278 residues), 164 bits, see alignment E=2.3e-52 TIGR00893: D-galactonate transporter" amino acids 19 to 411 (393 residues), 397.6 bits, see alignment E=3e-123

Best Hits

Swiss-Prot: 86% identical to EXUT_ECOLI: Hexuronate transporter (exuT) from Escherichia coli (strain K12)

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 100% identity to rah:Rahaq_3925)

MetaCyc: 86% identical to hexuronate transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-123; TRANS-RXN-35

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (430 amino acids)

>EX31_RS12670 MFS transporter (Rahnella sp. WP5)
MGKIKGLRWYMIALVTCGTVLGYLTRNAIAAAAPTLMSQLNITTQQYSYIIAAYSACYTL
MQPVAGYVLDVMGTKVGYAMFAIMWAIFCMATALASSWGGLAIARGAVGMAEAAMIPAGL
KASSEWFPAKERSIAVGYFNVGSSIGGMIAPPLVVWCIVMHSWQLAFIITGVLSLIWALS
WLVFYKHPKDQKKLSAEERTYILEGQEAQHQTNNGKKMSAWQILRNRQFWGIALPRFLAE
PAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQKYFKVNLIV
SRKMVVTMGAVLMIGPGMIGLFTSPYAAIALLCVGGFAHQSLSGALITLSSDVFGRNEVA
TANGLTGMAAWMASTMFALVVGALADTIGFSPLFAALAVFDLLGAIIIWTVLQNRSAVEP
VPAPLKTAKA