Protein Info for EX31_RS12605 in Rahnella sp. WP5

Annotation: type II secretion system protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details PF07963: N_methyl" amino acids 5 to 27 (23 residues), 28.9 bits, see alignment (E = 6.1e-11) TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 8 to 26 (19 residues), 23.3 bits, see alignment (E = 2e-09) PF21444: CofB_pilin_dom" amino acids 45 to 286 (242 residues), 103 bits, see alignment E=2.2e-33

Best Hits

KEGG orthology group: None (inferred from 100% identity to rah:Rahaq_3938)

Predicted SEED Role

"Toxin co-regulated pilus biosynthesis protein B" in subsystem Toxin co-regulated pilus or Vibrio pathogenicity island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (555 amino acids)

>EX31_RS12605 type II secretion system protein (Rahnella sp. WP5)
MPGVRNSKGFTLLEMIIVMGIMGVVFTSFSLYKKKQIESVARENLTNILAGEIHGFLQFV
NKDNIQLTTDVDADGELDFIVNPLYNPDILTSDEKGKAYATRFNNKPNEEPGDKNDYIKW
DNTQARGYFTSHRCYSSTNQKVADDEFNTEDLPCKQPPDSQDKYLVLERVDLIGPDNSRA
IDQVDFFISFHPGRNGKSDVDKFSIENYATAFSKAFSHYDLTFIQADYLYRNDEKNTQAT
NFGTGWKLLKTNNAKATDSAIPFGSMASYLDDMNQNIAQLGVRFSFKAGVGKNVKPDGSV
GVNKLCWNYKENMMTHCLEVENGSGRNQDEGVMHLTAKNANNQIVTGTLMANVIFEGEAF
DPEKGNVVALMTSPVVSYQSFGNKKDTGTNDVIVNDPENYNKKVTDEPGHIKLPVQTCPL
APPDPADPQKVPRQLYPRMAAAISSIAADVGKLETSEGEDEDGGDFTDFSNSENNRRTTT
GVLDHLSGVAVQVNLIKDDANGDYWVISATSGVFDNVTGQGVSVINPSSLSVVLTSWCSS
IKQPELDAHVPMPPD