Protein Info for EX31_RS12145 in Rahnella sp. WP5

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 transmembrane" amino acids 34 to 59 (26 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 100 to 118 (19 residues), see Phobius details amino acids 128 to 149 (22 residues), see Phobius details amino acids 161 to 184 (24 residues), see Phobius details amino acids 196 to 221 (26 residues), see Phobius details amino acids 234 to 252 (19 residues), see Phobius details amino acids 293 to 317 (25 residues), see Phobius details amino acids 336 to 354 (19 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 158 to 254 (97 residues), 69.5 bits, see alignment E=1.5e-23 PF00528: BPD_transp_1" amino acids 175 to 362 (188 residues), 85.2 bits, see alignment E=2.4e-28

Best Hits

Swiss-Prot: 82% identical to YHDY_ECOLI: Inner membrane amino-acid ABC transporter permease protein YhdY (yhdY) from Escherichia coli (strain K12)

KEGG orthology group: K09971, general L-amino acid transport system permease protein (inferred from 99% identity to rah:Rahaq_4032)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltK (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (369 amino acids)

>EX31_RS12145 amino acid ABC transporter permease (Rahnella sp. WP5)
MTMTTLPPGVRAVKSGTPLGTAVLWARKNLFSSWFNSLLTLFCLWLMWLLIPPLLNWVIF
QANWVGTARTDCTKAGACWVFIHARFGQFMYGLYPFDQRWRINVTLIVGLLTLAPIFFKA
MPRRGRYIACWMVLFPIFTWIMLYGGFLGLSRVETRQWGGLTLTLIIAAVGIAGALPLGI
MLALARRSSLPVVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMTEGTSIDKLVRALVGV
VLFQSAYVAEVVRGGLQALPKGQTEAAESLALGYWKTQGLVILPQALKMVIPGLVNTIIA
LFKDTSLVIIIGLFDLFSSVQQATVDPEWLGMSTEGYVFAAAVYWIFCFSMSRYSQHLER
RFHTGRSAH