Protein Info for EX31_RS12085 in Rahnella sp. WP5

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 362 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF01497: Peripla_BP_2" amino acids 49 to 302 (254 residues), 99.9 bits, see alignment E=7.6e-33

Best Hits

Swiss-Prot: 63% identical to Y1472_HAEIN: Uncharacterized protein HI_1472 (HI_1472) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 99% identity to rah:Rahaq_4044)

Predicted SEED Role

"Iron(III) ABC transporter, solute-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (362 amino acids)

>EX31_RS12085 ABC transporter substrate-binding protein (Rahnella sp. WP5)
MRLFSSRFLPAVALLGLALSLASPCAFATRQITDQLGRQVTIPDQVDRVVVLQHQTLNLL
VQLDATKDIVGVLNNWQRQLGSGYVRLAPELAKTPVVGDLTSVNLESVVALHPQVVFVTN
YAPQEMIDQISQAGIAVVAVSLRDDPKGEEHMMNPVLPDEDEAYTEGLKKGIALIGDVVN
HQKQAQALIDYTFSQRQLTGERLKDIPANQRIRTYMANPDLTTYGSGKYTGLMMAHAGAM
NVAAATVKGFKQVALEQVIAWNPQVIFVQDRYPEVVGQITGDPKWQGIDAVKNHRVYLMP
EYAKAWGYPMPEAMAIGELWMAKKLYPQKFADIDMQKQADAWYQRFYRTDFKPAADAARA
GK